Schedule Sep 9-12th

Schedule
September 9th, 2015 (Wednesday)
18:30-20:00h Registration "Envases de Cartón" Building
20:00h Welcome Cocktail "Sabatini" Building


September 10th, 2015 (Thursday)
8:00-8:40h Registration "Envases de Cartón" Building
8:40-9:00h Conference Opening
Plenary sessión I (Chair: Collin Watts) ("Envases de Cartón" Building)
9:00-9:40h
Martin J. van den Bent
Glioblastoma: how to fill this gap between basic science and clinical practice?
9:40-10:20h
Joan Seoane:
Evolution of the intratumor heterogeneity in glioblastoma in response to treatment
Coffee break and poster session (Building 1)

Oral communications
Chair: Ander Matheu
Basic mechanisms

(Envases de cartón building)
Oral communications
Chair:Marta Alonso
Novel clinical approaches

(Sabatini building)
10:50-11:10h
Maija Hyvönen
The role of MDGI in gliomas.
Philippe Schucht
Intraoperative monopolar mapping during 5-ALA-guided resections of glioblastomas adjacent to motor …
11:10-11:30h
Roberto Ferrarese
A novel integrative network model identifies ANXA2 as an epigenetically controlled …
Victor M. Pérez García
Prognostic and predictive significance of geometric measures based on pretreatment T1+Gd MR images in glioblastoma multiforme
11:30-11:50h
Elisabeth Stoll
Fatty acid oxidation is required for the respiration and proliferation of malignant …
Nabil Ahmed
A phase I Clinical Trial of Autologous HER2 CMV Bispecific Chimeric Antigen Receptor T …
11:50-12:10h
Ander Matheu
Role of SOX9 in Glioblastoma.
Lin Yung-Ya
Early GBM Detection by Active-Feedback MRI.
Break

Oral communications
Chair: J. L. Fernández-Luna
Angiogenesis
(Envases de cartón building)
Oral communications
Chair: Bárbara Meléndez
Novel clinical approaches
(Sabatini building)
12:20-12:40h
Roland E. Kälin 
Apelin signaling controls glioblastoma neo-vascularization
Mario Durán
Control of the redox balance in glioblastoma multiforme: impact on metabolism, neovascularization …
12:40-13:00h
O. Van Tellingen
Glioblastoma and the blood-brain barrier; please do not neglect. 
Aurélie Henry
Osteopontin as a new target in glioblastoma progression and resistance to radiotherapy.
13:00-13:20h
Julie Gavard
Endothelial Apenin employs APJ and gp130 to sustain glioblastoma stem cells.
Carmen Ramírez-Castillejo
In vivo evidences for the therapeutic effectiveness of Dacomitinib in glioblastoma.
13:20-13:40h
Anna Lisa Iorio
Opioid pretreatment alters blood-brain barrier penetration of doxorubicin in animal models …
Perrine Dahan
Ionizing radiations sustain Glioblastoma cell dedifferentiation to a stem …
Lunch
Plenary sessión II (Chair: Martin van der Bent) ("Envases de Cartón" Building)
15:30-16:10h
Wolfang Wick:
Biomarker-driven decision in the management of gliomas
16:10-16:50h
Kristin Swanson:
Patient-specific Mathematical Neuro-Oncology: The Drive Towards Precision Medicine
Coffe break and poster session (Building 1)

Oral communications
Chair: Massimo Squatrito
GBM invasiveness

(Envases de cartón building)
Oral communications
Chair: GF Calvo
Mathematical models
(Sabatini building)
17:10-17:30h
Jose Luis Fernández Luna
Teneurins increase the invasive capacity of GBM stem-like cells
Sergei Fedotov
Superdiffusive dynamics of cancer cells
17:30-17:50h
María Alieva
Intravital imaging reveals local effects of biopsy on glioma cell migration
Y. Admiralskiy and A. Bratus
Hybrid cellular automaton model of tumor growth
17:50-18:10h
Geraline O´Neill
GBM brain cancer invasion: how different subclasses move through the brain.
Rui Travasso
The force at the tip: modelling tension and proliferation in sprouting angiogenesis.
Break (*See social program)


September 11th, 2015 (Friday)
Plenary session III (Chair: Joan Seoane) ("Envases de Carton" Building)
8:30-9:10h
Simone Niclou
Regulation of oxidative stress pathways in IDH1 mutant gliomas (EACR sponsored talk)
9:10-9:50h
Colin Watts
Surgical strategies to interrogate the genomic of glioblastoma
9:50-10:30h
 Roel Verhaak
Genomic characterization of disease evolution in glioma
Coffee break and poster session (Building 1)

Oral communications
Chair: Pilar Sánchez
Novel therapeutical approaches
(Envases de cartón building)
Oral communications
Chair: Victor Pérez 
(Sabatini building)

11:00-11:20h
Francesca Maule
Annexin A2 is a key determinant of GBM aggressiveness by controlling cancer cell dissemination and proliferation.
Bárbara Meléndez
Clinical and Molecular features of Long-term Survivors with glioblastoma
11:20-11:40h
Bárbara Oldrini 
RanBP6 is a novel tumor suppressor that negatively regulates EGFR
Guillermo Velasco 
Towards the utilization of cannabinoids as anti-cancer agents in glioma.
11:40-12:00h
Irene Ylivinkka
Netrin-1 induced activation of Notch signaling regulates glioblastoma cell pathogenity
Andreas Hottinger
EF-14 Study : Efficacy of alternating electrical fields combined with Temozolomide vs Temozolomide alone in patients with newly diagnosed GBM
Break

Oral communications
Chair:  Angel Ayuso
Novel therapeutical approaches
(Envases de cartón building)
Oral communications
Chair: J. Belmonte-Beitia
Mathematical models
(Sabatini building)
12:30-12:50h
Amanda Tivnan
Inhibition of Multidrug Resistance Protein I (MRP1) improves chemotherapy drug …
Christina Surulescu
Mathematical models for glioma invasion: Multiscality, proliferation, and treatment. 
12:50-13:10h
Sourav Ghosh
Simultaneously targeting cell autonomous and non-cell autonomous oncogenic … 
Elena Fimmel
Viable therapy strategies in a spatial mathematical model of Glioma with consideration …
13:10-13:30h
Marcos García-Fuentes
Nanostructured microspheres for the controlled release of BMP-7 and the suppression of .. 
Andreas Deutsch
Analyzing emergent behaviour in cellular automaton models of glioma invasion.
Lunch
Plenary session IV (Monika Hegi) ("Envases de Carton" Building)
15:30-16:10h
Bozena Kaminska
Targeting tumor-derived integrin ligands modulate immune microenvironment of glioblastoma: a novel therapeutic approach
 

16:10-16:50h
Frank Winkler
Multidimensional intravital microscopy discovers a novel mechanism of progression and resistance in glioblastoma
Coffe break and poster session (Building 1)

Oral communications
Chair: Carla Boccacio
Basic mechanisms

(Envases de cartón building)
Oral communications
Chair: Iñaki Ochoa
Quantitative approaches
(Sabatini building) 
17:10-17:30h
Elena Rampazzo
Wnt pathway intracellular effectors are key deciders of GBM cell phenotype and behaviour.
Luis Fernández
Novel in-vitro biomimetic microfluidic device to resemble the glioblastoma microenvironment.
17:30-17:50h
Anna-Maria Barciszewska  
Uncovering the action of Temozolamide in brain tumor cells. 
Christophe Deroulers
Quantitative models of low-grade glioma: from the laws of infiltration in diffuse gliomas to a model of radiotherapy.
17:50-18:10h
Ian Lorimer
Glioblastoma as a disease of asymmetric cell division. 
Anton Buzdin
OncoFinder, a family of new methods for the analysis of complex intracellular signaling …
18:10-18:30h
Kumar Somasundaram
Tumor-stroma interaction in glioma through proteomic approaches. 
Olivier Saut  
Effects of anti-angiogenesis on glioblastoma growth and migration. Model to clinical predictions 
Break (*See social program)


September 12th, 2015 (Saturday)

Oral communications VII-1
Chair: Jose Antonio Costoya
Biomarkers
(Envases de cartón building)
Oral communications VII-2
Chair: Andreas F Hottinger
Novel clinical approaches
(Sabatini building)
9:20-9:40h
Angel Rodríguez de Lope
Clinical and molecular factors predict survival after surgery for recurrent glioblastoma multiforme
Sergio Casas-Tintó
Synaptogenesis to prevent glioblastoma-induced neurodegeneration
9:40-10:00h
Danilo Fiore
Survival in glioblastoma patients is predicted by miR-340 that regulates key cancer … 
Anthony Falkov  
Reirradiation of relapsed Glioblastoma.
10:00-10:20h
Marta Alonso
Alternative splicing of BAF45d contributes to the pathogenesis of GBM.
Aleck Hercbergs
Medically induced euthyroid hypothyroxinemia may improve outcomes in glioblastoma …
10:20-10:40h
Paola Parrella
Identification of miR21 and miR210 as biomarkers of aggressive clinical behaviour …
Maurizio Lucchesi
Temozolomide and Valproinic acid for treatment of pediatric high-grade gliomas …
10:40-11:00h
Maria Stella Carro
ZBTB18 Methylation promotes mesenchymal transformation in glioblastoma.
 Semi Ben Harrabi
Radiotherapy plus Concomitant Temozolomide in Primary Gliosarcoma.
Coffee break
Plenary session V (Chair: Bozena Kaminska ) ("Envases de Carton" Building)
11:30-12:10h
Carla Boccacio
The MET oncogene as a functional marker and therapeutic target in glioblastoma stem cells.
12:10-12:50h
Monika Hegi
Epigenic deregulation in glioma, biomarkers and new opportunities.
12:50:13:30h
Guido Reinfenberger
Who´s next: Integrated morphological and molecular classification on gliomas.
13:30-13:45h
Closing remarks
13:45-15:00h
Lunch

*Social program
September 10th, 2015 (Thursday)
19:30h
Toledo tour and dinner. Departure from Plaza Zocodover.
September 11th, 2015 (Friday)
19:45-20:30h
Concert (Patio de Covarrubias, San Pedro Mártir)
September 11th, 2015 (Friday)
20:45-21:00h
Departure to the conference dinner ( by buses from Cuesta de Carlos V )